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Omicron subvariants escape antibody responses: study

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  • Subvariants can escape antibody responses among those who had contracted COVID-19 and those who are vaccinated, boosted. 
  • Vaccination is expected to provide substantial protection against coronavirus.
  • Study shows it may also increase “risk of vaccine-breakthrough COVID-19 infections.”

A new study shows that the Omicron subvariants BA4 and BA5 can escape antibody responses among people who had contracted COVID-19 and those who have been vaccinated and boosted. 

However, the vaccination is expected to provide substantial protection against coronavirus.

Meanwhile, the vaccine makers are also working on upgraded shots that may evoke a stronger immune response against the subvariants, CNN reported. 

According to the new research published in the New England Journal of Medicine, compared with the original coronavirus, the levels of neutralising antibodies that a previous infection or vaccinations elicit are several times lower against the BA4 and BA5 subvariants. 

“We observed three-fold reductions of neutralizing antibody titers induced by vaccination and infection against BA4 and BA5 compared with BA1 and BA2, which are already substantially lower than the original COVID-19 variants,” wrote Dr Dan Barouch, who is an author of the paper. 

“Our data suggest that these new Omicron subvariants will likely be able to lead to surges of infections in populations with high levels of vaccine immunity as well as natural BA1 and BA2 immunity,” he added. 

The findings are separate researches by scientists at Columbia University, according to which, the escaping of BA4 and BA5 viruses also increases the “risk of vaccine-breakthrough COVID-19 infections.”

Their studies also suggest an increased risk of reinfection, among those people who had been immunised against the virus. 

European Centre for Disease Prevention and Control said that the subvariants are reported to be fast-spreading ones, which are expected to dominate the United States, United Kingdom and the rest of Europe in the upcoming few weeks. 

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Five IPP contracts are being terminated, according to PM Shehbaz.

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He stated that this was carried out with the owners of the IPPs’ mutual approval while presiding over today’s federal cabinet meeting in Islamabad.

The Prime Minister notified the Cabinet that no interest will be paid; only the remaining sums owed to these IPPs will be settled.

He emphasized that breaking these contracts will benefit the national exchequer by around 411 billion rupees and save power users roughly sixty billion rupees.

Shehbaz Sharif claimed that it was the result of the government team’s tireless efforts working together. In this regard, he acknowledged the associated parties’ contributions and support as well. In particular, he brought up General Asim Munir, Chief of Army Staff, who showed a personal interest in the entire situation.

The Prime Minister explained that the breakthrough marked the start of a path that will ultimately lead to the wealth and advancement of the populace.

Shehbaz Sharif also brought up the assistance given to power users in the summer by the Punjabi and Federal governments.

The prime minister expressed happiness that the economy is steadily approaching stability. He made note of the fact that remittances for the first quarter reached a record-breaking $8.8 billion. This indicates that Pakistan’s economy is progressing, he remarked.

The administration, according to Shehbaz Sharif, also took action to lower the inflation, which is currently only one digit. He said that this was the PML-N’s election manifesto pledge being fulfilled.

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Special Jirga for Peace in KP: Consultation of Parliamentary Leaders During the Jirga

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Governor of Khyber Pakhtunkhwa Faisal Karim Kundi departed for Peshawar to take part in the special jirga on the political and peace conditions in the province.

He was asked to participate in the jirga, which was called by the Provincial Assembly to discuss provincial matters, by Khyber Pakhtunkhwa Chief Minister Ali Amin Gandapur.

Following discussions with the parliamentary leaders of all of the Provincial Assembly’s political parties, this Jirga has been called.

According to Ahmed Karim Kundi, a Pakistan People’s Party provincial assembly member, Khyber Pakhtunkhwa’s predicament worries all of the province’s major groups.

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The Interior Minister is scheduled to attend the Grand Jirga in Peshawar.

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To examine the political and security situation, Mohsin Naqvi, the federal minister of interior, will be present at the Grand Jirga in Peshawar.

Chief Minister of Khyber Pakhtunkhwa Sardar Ali Amin Gandapur is hosting the Grand Jirga, which will take place at the Chief Minister House in Peshawar.

This jirga is intended to examine the province’s present political and security landscape and develop a collective action plan.

Discussing the issues that surfaced following the Pakhtun Jirga, which was organized by the outlawed Pashtoon Tahafuz Movement, is the purpose of the current Jirga.

Political party leaders, tribal elders, and members of the Provincial Assembly Khyber Pakthunkhwa will also be present at the Jirga.

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