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Can weight-loss injections make you suicidal? Here’s what we know

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The European Medicines Agency (EMA) has said it is reviewing some weight-loss injections after receiving information that the jabs were linked to suicidal thoughts and self-harm among users, BBC reported.

Iceland, a member state, informed the European drug regulator after it saw three cases, with the EMA set to look at Wegovy, Saxenda and similar drugs — which help reduce a person’s appetite.

Although product leaflets list suicidal thoughts as a possible side effect, suicidal behaviour isn’t listed for “these prescription drugs”.

“The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC), which is conducting the review, will consider whether other treatments in same broader category of medicines, glucagon-like peptide-1 (GLP-1) receptor agonists, also need assessing,” the British broadcaster reported.

Initially, the drug regulator will assess the risks of the medication that contains semaglutide or liraglutide.

“The review is being carried out in the context of a signal procedure raised by the Icelandic Medicines Agency, following three case reports,” an EMA official said.

“A signal is information on a new or known adverse event that is potentially caused by a medicine and that warrants further investigation.

“The case reports included two cases of suicidal thoughts – one following the use of Saxenda and one after Ozempic.

“One additional case reported thoughts of self-injury with Saxenda.

“The EMA will communicate further when more information becomes available.”

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Nineth round of political talks between Pakistan and the EU centers on trade and security

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In their ninth round of political dialogue, which took place here on Wednesday, Pakistan and the EU discussed all aspects of their bilateral relationship, with a particular emphasis on the Strategic Engagement Plan (SEP), trade and development cooperation, security, climate action, migration, and mobility.

The team from Pakistan was led by Foreign Secretary Muhammad Syrus Sajjad Qazi, while Enrique Mora, Deputy Secretary General of the European External Action Service, represented the EU.

Significant local and international happenings were also covered.

The two parties expressed satisfaction with the positive direction of the relationship and decided to keep working to expand and deepen bilateral ties between Pakistan and the EU in all areas of shared interest. They will do this by routinely convening institutional mechanism meetings and carrying out follow-up tasks.

The two sides acknowledged the significance of bilateral relations between Pakistan and the EU, concurring that frequent high-level meetings have given the relationship new life and emphasized the need for close communication and collaboration in the face of a geopolitical environment that is changing quickly.

In order to bring about diversification and sustainability in trade ties between Pakistan and the European Union, the Foreign Secretary emphasized the need for deeper collaboration with key stakeholders on both sides, acknowledging GSP Plus as a successful model of trade for development and mutually beneficial cooperation.

The two parties also decided to investigate fresh prospects under the EU’s major initiatives, Horizon Europe and the Global Gateway Strategy.

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Traval

In Canada, another member of the PIA crew disappears.

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Jibran Baloch, a flight attendant, is the second PIA air hostess to vanish this month; she was scheduled to take a Toronto trip from Karachi and then left the hotel.

Flight 782 failed to arrive for its planned return duty on February 29. Jibran Baloch, a flight attendant, is the second air hostess to go this month.

When staff members searched Jabran Baloch’s room, they discovered that he had fallen. Another missing person from the hotel a few days earlier was a female air hostess. In just a few months, almost 12 air hostesses who were assigned to flights to Toronto had vanished.

A Pakistan International Airlines (PIA) flight hostess is said to have vanished from her job in Canada earlier this month.

When Maryam Raza, who was supposed to be on aircraft PK 782 from Pakistan to Toronto, neglected to show up for work on the return trip, PK 784 from Toronto to Karachi, the event became public knowledge. According to those with knowledge of the situation, after PIA’s hanging uniform was found in her room, a letter with the words “Thank you, PIA” was found next to it.

This is the third instance of PIA flight attendants’slipping’ while on duty that has been documented this year; two of the cases involve women.

The efficacy of these procedures has not increased despite steps taken to prevent similar instances, such as obtaining the passports of flight attendants assigned to Toronto flights.

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Pakistan

China “agrees” to transfer $2 billion in debt to Pakistan.

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ISLAMABAD China has “agreed” to roll over a $2 billion loan to Pakistan, according to sources cited by ARY News, which is a big milestone.

Sources inside the ministry of finance claim that the $2 billion loan will be rolled over under the current terms prior to its maturity date.

Less than 2 percent interest will be charged on the $2 billion in Chinese debt that is being deposited, according to sources.

According to reports, the $2 billion debt’s maturity period will conclude on March 23, 2024, and an additional $2 billion will be rolled over for a year.

It is important to note that as of the end of November in FY2023–24, Pakistan’s overall debt load was at an astounding Rs 63,399 trillion.

Over Rs12.430 trillion more was borrowed by the nation during the PDM and caretaker government’s mandate.

With domestic loans totaling Rs40.956 trillion and foreign loans totaling Rs22.434 trillion, Pakistan’s total debt load increased to Rs63.390 trillion.

China postponed paying Pakistan’s $2 billion debt for two years, starting in July 2023. Regarding the delay in debt recovery, Pakistan received an official letter from China Eximbank.

Pakistan will return the debt in accordance with the terms of the deal with China and was also spared from paying extra interest on the loan. According to further sources, all 31 loan agreements were extended over the original date of July 21, 2023, to June 30, 2025.

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